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Ocular invasion in sinonasal malignant melanoma: A case report and review of literature

B. Khademi, Sajjad Soltani, Alireza Yousefi, P. Heidari, Zhale Mardani, Shayan Yousufzai

International journal of surgery case reports, 2025

4 citations

Abstract

Background Sinonasal mucosal melanoma (SNMM) is a rare and aggressive malignancy associated a poor prognosis, prognosis. It is by delayed presentation and nonspecific symptoms. The incidence of SNMM is low, with and there are challenges in achieving local control and managing distant metastases. Case Presentation. We report present case of an 86-year-old female patient with a history of systemic hypertension who presented exhibited symptoms, including blurred vision, rhinorrhea, and facial pain, following initial treatment for SNMM. sinonasal mucosal melanoma (SNMM). studies revealed a heterogeneous lesion in the right nasal cavity and ethmoidal air cells, exhibiting characterized by destruction and invasion into the orbit. The patient underwent functional endoscopic sinus surgery (FESS) for resection, with and analysis confirming confirmed the diagnosis of melanoma. Discussion This case underscores the aggressive nature of SNMM and emphasizes importance of early diagnosis and intervention. Despite Although treatment with surgery and radiotherapy leading resulted in resolution for two years, the recurrence of symptoms highlights the challenges in associated with long-term control. The Effective of SNMM requires necessitates multidisciplinary approach, approach that includes resection and the of adjuvant therapies. Conclusion SNMM poses presents treatment challenges due to its aggressive behavior nature complex anatomical location. A comprehensive approach involving that…

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