Evidence Hub

A cross-sectional study comparing machine learning and logistic regression techniques for predicting osteoporosis in a group at high risk of cardiovascular disease among old adults

Yuyi Peng, Chi Zhang, Bo Zhou

BMC Geriatrics, 2025

211 participants · 18 citations

Abstract

Osteoporosis has become a significant public health concern that necessitates the application of appropriate techniques to calculate disease risk. Traditional methods, such as logistic regression,have been widely used to identify risk factors and predict disease probability. However,with the advent of advanced statistics techniques,machine learning models offer promising alternatives for improving prediction accuracy. What’s more, studies that use risk factors and prediction models for osteoporosis in high-risk groups for cardiovascular diseases are scarce. We aimed to explore the risk factors and disease probability of osteoporosis by comparing logistic regression with four machine learning models. By doing so,we seek to provide insights into the most effective methods for osteoporosis risk assessment and contribute to the development of tailored prevention strategies at high risk of cardiovascular disease among old adults. We carried out a cross-sectional investigation of a high-risk group in cardiovascular patients. A logistic regression model and four common machine learning methods,DT,RF,SVM,and XGBoost were implemented to create a prediction model using information from 211 participants who met the inclusion requirements. Metrics for calibration and discrimination were used to compare the models. In total,211 patients were enrolled. The AUCs were 0.751 for the logistic regression model,0.72 for the SVM model,0.70 for the random forest model,0.697 for the model…

How strong is the evidence?

Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 211 participants or records.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

Read the paper

Related studies

Go deeper in Evidence Hub

Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.

Open this study Sign up free