Personalized Remote Radiation Tracking Portable Organ Dosimetry Device (Prrt Podd): New Detector Design Investigations
Abstract
Introduction: This paper is an investigation of two new detector designs for the PRRT PODD. The overall goal of the project is to support radiopharmaceutical therapy personalization based upon dose to a patient's organs at risk and tumors. Methods: The original PRRT PODD detectors were spectroscopy probes that used a 14 mm cubic tungsten collimator with a 4 mm diameter pinhole. In retrospect, we believe given the weight of the collimator (i.e., 31.2 grams), it was "leaky" and allowed too many 208 keV photons outside the probe's cone of response to be detected. In this work, we investigate two new designs. The first is the gamma tube. It is very compact and weighs only 3.33 grams. The gamma tube is designed to measure both the 113 keV and 208 keV photons. Its collimator is very “leaky” to 208 keV photons but stops over 99.9 % of the 113 keV photons. We will use the counts from both the 208 keV and 113 keV energy windows to estimate activity in structures of interest. The second detector is an imaging detector. It is larger and weighs more; however, it also provides an image of the structure(s) it is viewing. Our aim is to use the image to enable detection and compensation for positional offsets of an organ or tumor between measurements. We used the SimSET Monte Carlo simulation package for this study. Results: The gamma tube provided a very well collimated sensitivity map of the 113 keV photon flux. The 208 keV energy window included a significant fraction of counts beyond…
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