Optical and magnetic properties of rare earth Doped α-Fe2O3 for future bio-imaging applications
Abstract
Imaging techniques have been developed for decades for the detection of biomolecules in \nbiomedicine cells, in vitro or in living cells and organisms. The application however, often \nconstrained by the available probes, whose optical properties may limit the imaging possibilities. \nIt is very essential to improve the sensitivity of these devices by enhancing efficiency to detection. \nRecently, Fe3O4 has been used primarily in cancer theranostic application such as magnetic \nresonance imaging (MRI). However, its toxicity towards normal cells has been pointed out by \nscientific communities, when they are involved in in vitro (helics) cancer treatment. In this work, \nwe have chosen to use α-Fe2O3, because it has proven to be less toxic than Fe3O4. Hematite is \nantiferromagnetic (AFM) at room temperature with a small canted moment lying within the crystal \nsymmetry plane. At low temperature, hematite undergoes a magnetic phase transition from weak \nferromagnetic (WFM) to a pure antiferromagnetic configuration (AF), which is known as the \nMorin transition. This magnetic property makes it possible for hematite to be applied in imaging \ntechnique. To enhance the optical properties, the α-Fe2O3 is doped with lanthanide ions due to their \nunique optical properties. Incorporation of these rare earth ions, enable the α-Fe2O3 to have \nenhance luminescence properties. \nImaging techniques have been developed for decades for the detection of biomolecules in \nbiomedicine…
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