The efficacy of combined bandage contact lens and nasal margin suture fixation in pterygium patients and its impact on inflammatory cytokines
Abstract
This study aims to evaluate the efficacy of combining bandage contact lens with nasal margin suture fixation in pterygium resection, as well as to observe its effects on the levels of inflammatory cytokines measured in tear samples. This randomized controlled research involved the selection of 80 patients (80 eyes) who underwent limbal conjunctival autograft (LCAG) procedures at Chengfei Hospital between June 2022 and June 2024. Subjects were allocated in a 1:1 ratio to two groups: group 1 utilized bandage contact lens combined with nasal margin suture fixation, while group 2 employed bandage contact lens combined with traditional interrupted suture. Ultimately, 37 patients (37 eyes) in each group successfully completed all scheduled follow-up assessments. The evaluation indicators include operative time, Visual Analog Scale (VAS) scores, thickness of limbal-conjunctival autograft, levels of inflammatory cytokines in tears such as interleukin-6 (IL-6) , tumor necrosis factor α (TNF-α) , and transforming growth factor beta1 (TGF-β1) , as well as postoperative complications. Group 1 exhibited a significantly greater reduction in operative time compared to Group 2 (t = - 3.921, P 2 = 0.237, 0.063, 0.084; P = 0.626, 0.802, 0.772). In group 2, only one patient with T3 (2.70%) experienced recurrence. The combination of bandage contact lens and nasal margin suture fixation is a safe and effective method for treating pterygium. Its efficacy is associated with the reduction of…
How strong is the evidence?
Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design. Reported size: 80 participants or records.
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