Development of a Novel Truncated-correlation Photothermal Coherence Tomography for Non-invasive Biothermophotonic and Non-destructive Materials Imaging
Abstract
Truncated-Correlation Photothermal Coherence Tomography (TC-PCT) is the most successful class of diffusion-wave methodologies to-date providing 3-D subsurface visualization. To extend depth range and axial and lateral resolution, a novel imaging system with improved instrumentation, and an optimized reconstruction algorithm over the conventional TC-PCT technique is developed in this PhD project. The enhanced TC-PCT system was then used for biomedical and non-destructive testing applications. First, we reported visualization of subsurface defects in a steel sample. The results demonstrate defect detection at the depth range of ∼4 mm in a steel sample, which exhibits dynamic range improvement by a factor of 2.6 compared to the conventional TC-PCT, the Lock-in Thermography and Thermal Wave radar. Lateral resolution in the steel sample was measured to be ∼ 31 μm. Second, we used the system to investigate the possibility of non-destructive imaging of an art object to identify features that often are invisible areas of vulnerability and damage. The enhanced TC-PCT modality identified all the defects such as empty holes, a hole filled with stucco, delaminations and natural features such as a wood knot and wood grain in different layers of the sample. The system was then used for biomedical applications, three of which are early demineralization in tooth sample, early detection of tumor in mice, and structural imaging of mouse brain. First, we introduced dental enhanced TC-PCT…
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