Characteristics of levofloxacin and its clinical application (review)
Abstract
We analyzed of the effectiveness of levofloxacin in various diseases, the sensitivity of microorganisms to it and side effects. LF does not show carcinogenic, mutagenic and teratogenic activity. It is used effectively in the treatment of infections of the respiratory and genitourinary tract, skin and soft tissues, for the prevention of complications in surgical practice, as well as infections of many other localizations. Levofloxacin has a wide spectrum of action, including most gram-positive and gram-negative pathogens, including intracellularly located, unlike other fluoroquinolones, highly active against gram-positive cocci, including pneumococci which are resistant to penicillin, erythromycin. In addition, levofloxacin is more active against atypical pathogens. Doctors should clearly justife the appointment of LF in an adequate dose in each case, in order to avoid or reduce the occurrence of resistance of pathogens to it.
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