Beyond Benefits of Q10: Mitochondrial Cocktail for Gulf War Illness
Abstract
The purpose of this study is to develop preliminary evidence, such as effect size and variance estimates, to guide successful conduct of a properly-powered clinical trial to assess the benefit of a mitochondrial cocktail (incorporating individualization of treatment) in Gulf War illness (GWI).
Conditions: Gulf War Syndrome, Persian Gulf Syndrome, Mitochondrial Disorders.
Primary outcome: Mean change in single item General Self-Rated Health Visual Analog Scale from baseline; Percent improved on Gulf War Illness Modified Lower Extremity Performance Score/timed chair rises; Number of symptoms (out of 20 on the UCSD Symptom Score Survey) showing more favorable change (trend or effect) on active treatment vs. placebo; Mean change of CoQ10 and Vitamin E levels, comparing active treatment to placebo.
Enrollment: 15 participants.
How strong is the evidence?
Evidence Hub reads this as a clinical trial, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 15 participants or records.
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