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Therapeutic Benefits of Topical Omega‐3 Polyunsaturated Fatty Acids in Skin Diseases and Cosmetics: An Updated Systematic Review

L. Mateu-Arrom, Ignasi Mora, Leia Garrote

Journal of Cosmetic Dermatology, 2025

11 citations

Abstract

Oral supplementation with omega‐3 polyunsaturated fatty acids (ω‐3 PUFAs) has shown beneficial effects in some dermatologic diseases (i.e., atopic dermatitis, acne, psoriasis, burns), but the actual effect of local application of ω‐3 PUFAs for improving skin health is still under investigation.

How strong is the evidence?

Evidence Hub reads this as a systematic review. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

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