The combined effect of yoga and rich in omega-3 camelina sativa powder on glycemic indices, inflammation, and oxidative stress in women with type 2 diabetes mellitus: a randomized controlled trial
Abstract
Background: This trial evaluated the combined effect of yoga and camelina sativa powder (CSP) on glycemic indices, inflammatory and oxidative stress parameters in women with type 2 diabetes mellitus (T2DM).
Methods: In this trial, 80 patients with T2DM were randomly allocated into four groups: group 1 (placebo), group 2 (receiving CSP), group 3 (doing yoga), and group 4 (receiving CSP and doing yoga) for 8 weeks. Glycemic indices, inflammatory and oxidative stress parameters were assessed pre-and post-intervention.
Results: CSP plus yoga treatment significantly increased the McAuley-index and Quick-index compared to the placebo group (P = 0.021 and P < 0.001, respectively). A significant decrease in the glycemic exposure (GE) index (P = 0.010), fasting blood sugar (FBS) (P = 0.003), hemoglobin A1c (P = 0.013), insulin (P = 0.002), and homeostasis model assessment of insulin resistance (HOMA-IR) (P < 0.001) was found in the CSP plus yoga group compared to the placebo after adjustment for confounders. Serum superoxide dismutase level significantly increased in camelina, yoga, and both CSP plus yoga groups compared to the placebo group (P < 0.001, P = 0.019, and P = 0.005, respectively). Serum catalase levels increased significantly in CSP plus yoga group compared to the placebo following 8 weeks (P = 0.022). Malondialdehyde concentration declined significantly in yoga and CSP plus yoga groups compared to placebo (P = 0.017 and P < 0.001, respectively). Serum tumor necrosis…
How strong is the evidence?
Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design. Reported size: 80 participants or records.
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