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Effectiveness and cost-effectiveness of an online transdiagnostic positive psychology intervention for patients awaiting mental health treatment and their loved ones: study protocol

Zinzen J, van Hooren S, Drost RMWA, Kavelaars X, Rohrbach PJ, Thewissen V, Evers SMAA, Boselie JJLM

BMC psychology, 2025

1 citation

Abstract

Background: Mental healthcare is under pressure, resulting in prolonged waiting lists for treatment. This is problematic, as time spent on a waiting list is associated with suboptimal recovery, more treatment dropout, and increased societal costs. An online transdiagnostic positive psychology intervention (eHealth PPI) may increase resilience (i.e., the ability to adapt to challenging experiences) and well-being among patients. Offering the same intervention to loved ones could be a novel contribution to enhancing positive effects among patients and loved ones. A study protocol is presented aimed at examining the clinical effectiveness, cost-effectiveness and implementation procedures of an eHealth PPI for patients with various mental health complaints awaiting treatment and their loved ones.

Methods: Using two studies, the current manuscript proposes a threefold evaluation of an eHealth PPI consisting of 9 modules, focusing on: [1] clinical effectiveness, [2] economic evaluation, and [3] implementation procedures. To evaluate the procedural implementation of the eHealth PPI from a user-perspective, a replicated single-case design (RSCD) will be performed in study 1, with measurements at baseline, after each module, and post-intervention. In study 2, a randomized controlled trial (RCT) will be used to examine the clinical effectiveness, cost-effectiveness and implementation procedures of the eHealth PPI, using three arms: [1] PPI during the waiting period for patients, [2]…

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Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design.

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