An exploratory study of before hospitalization nutrients associated with N-terminal pro b-type natriuretic peptide during the exacerbation of chronic heart failure
Abstract
Background & aims: In patients with chronic heart failure (CHF), insufficient salt/fluid restriction is the most frequent problem necessitating re-hospitalization, and its prevention represents a challenge in nutrition management. However, the quantities involved have yet to be established, and in particular, the relationship between the detailed dietary status before and after hospitalization has not been characterized. In this study, we aimed to assess the dietary habits of patients before hospitalization and exploration analysis to identify the nutrients associated with N-terminal pro b-type natriuretic peptide (NT-proBNP) during the exacerbation of CHF.
Methods: We performed a cross-sectional study of elderly patients allocated to two groups according to their NT-proBNP concentration at the time of hospitalization, using a cut-off value of 2,000 pg/mL. Categorical datasets were compared using the χ2 test or Fisher's exact test, and continuous datasets were compared using the Wilcoxon rank-sum test. Furthermore, multivariate logistic regression analysis was performed using an NT-proBNP concentration >2,000 pg/mL as the dependent variable and the n-3 polyunsaturated fatty acids, alpha-tocopherol, vitamin B1, vitamin D, zinc, iron, potassium, magnesium, salt equivalent, and fluid status, and the propensity score (PS), estimated glomerular filtration rate (eGFR) and HFpEF as explanatory variables.
Results: Data for 63 patients were analyzed. Their overall median age was 82…
How strong is the evidence?
Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 63 participants or records.
Read the paper
Related studies
- eggNOG 5.0: a hierarchical, functionally and phylogenetically annotated orthology resource based on 5090 organisms and 2502 viruses
- Online Survival Analysis Software to Assess the Prognostic Value of Biomarkers Using Transcriptomic Data in Non-Small-Cell Lung Cancer
- OptiType: precision HLA typing from next-generation sequencing data
- Nicotinic Cholinergic System and COVID-19: In Silico Identification of an Interaction between SARS-CoV-2 and Nicotinic Receptors with Potential Therapeutic Targeting Implications
- Saccharomyces cerevisiae cells have three Omega class glutathione S-transferases acting as 1-Cys thiol transferases
- Hemolysis at low blood flow rates: in-vitro and in-silico evaluation of a centrifugal blood pump
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.