Gestational Hypertriglyceridemia Management and the Utility of Multidisciplinary Care
Abstract
Background: Severe hypertriglyceridemia (HTG) in pregnancy can lead to adverse outcomes such as preeclampsia, preterm delivery, and pancreatitis. However, there are no official management guidelines for gestational HTG.
Case summary: A 33-year-old woman at 32 weeks of gestation presented to the lipid clinic for severe HTG. With a multidisciplinary care team, a treatment plan including fenofibrates and icosapent ethyl was initiated. The treatment plan successfully reduced triglycerides and led to an uncomplicated delivery.
Discussion: Gestational HTG can pose severe risks to pregnant patients. Limited safety data exist on treatment options in pregnant patients; thus there are no official management guidelines for treating this condition. Future work is needed to establish official guidelines for gestational HTG and preconception counseling to protect the mother and fetus.
Take-home message: Given the treatment barriers of HTG in this vulnerable population, we present a case where multidisciplinary care successfully managed severe HTG in pregnancy.
How strong is the evidence?
Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
Read the paper
Related studies
- eggNOG 5.0: a hierarchical, functionally and phylogenetically annotated orthology resource based on 5090 organisms and 2502 viruses
- Online Survival Analysis Software to Assess the Prognostic Value of Biomarkers Using Transcriptomic Data in Non-Small-Cell Lung Cancer
- OptiType: precision HLA typing from next-generation sequencing data
- Nicotinic Cholinergic System and COVID-19: In Silico Identification of an Interaction between SARS-CoV-2 and Nicotinic Receptors with Potential Therapeutic Targeting Implications
- Saccharomyces cerevisiae cells have three Omega class glutathione S-transferases acting as 1-Cys thiol transferases
- Hemolysis at low blood flow rates: in-vitro and in-silico evaluation of a centrifugal blood pump
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.