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Efficacy of Traditional Chinese Medicine in Reducing Readmission in Elderly Patients with Community-Acquired Pneumonia

Jian-Sheng Li, Ming-Hang Wang, Peng Zhao, Weihong Han, Yang Xie, Huiyong Zhang, Jun-Chao Yang, Lei Wu et al.

Journal of Ethnopharmacology, 2025

292 participants · 2 citations

Abstract

ETHNOPHARMACOLOGICAL RELEVANCE

Elderly patients with community-acquired pneumonia (CAP) often exhibit non-respiratory symptoms, which can lead to readmission, increased mortality risk. Traditional Chinese medicine (TCM) treatments for elderly CAP patients have been shown to reduce rehospitalization rates.

AIM OF THE STUDY

This work aims to evaluate the efficacy of TCM treatment in reducing the rehospitalization rate of elderly patients with CAP post-discharge.

MATERIALS AND METHODS

The clinical efficacy of TCM formulae, including Bufei Jianpi Huatan formula (BJHF) and Yiqi Yangyin Qingfei formula (YYQF), was evaluated in a randomized controlled trial involving 292 patients across seven centers. Within one week after discharge, elderly patients with community-acquired pneumonia were randomly divided into an experimental group and a control group.

RESULTS

A total of 292 elderly CAP subjects were included in this study. After 2 months of treatment and 6 months of follow-up, 33 cases were lost (13 in the experimental group and 20 in the control group). Consequently, 259 patients (133 in the experimental group and 126 in the control group) were subjected to statistical analysis. No significant differences were observed in gender, ethnicity, marital status, or other baseline characteristics between the two groups. The BJHF and YYQF treatments significantly reduced the rehospitalization rates for pneumonia in elderly patients with CAP (P=0.027; 0.035; 0.041). However, there was no…

How strong is the evidence?

Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design. Reported size: 292 participants or records.

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