Evidence Hub

Experimentally tractable, pseudo-elastic constitutive law for biomembranes: I. Theory

Criscione JC, Sacks MS, Hunter WC

Journal of biomechanical engineering, 2003

Abstract

Although visco-elastic in general, the stress-strain relation of biomembranes is one-to-one or pseudo-elastic when being loaded after preconditioning. This pseudo-elastic relation is hypoelastic (i.e., it is not hyperelastic), yet much of the stress response can be characterized by a scalar function omega that represents the work done (per unit reference volume) on the specimen during loading. (Since a pseudo-strain-energy function W is optimized to fit the test data and not the work done, omega is not equal to W in general.) The remaining part tR of the stress response does no work during loading. With biaxial testing, omega can be definitively determined from data. Moreover, for tests with the stretch directions coaxial to the axes of anisotropy, tR can be accurately characterized by a scalar function omega that depends on the strain. This paper is part 1 of 2 with "I. Theory" and "II. Application."

How strong is the evidence?

Evidence Hub reads this as a theoretical / analytical, done in animal and computer models (in silico), not in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

Read the paper

Related studies

Go deeper in Evidence Hub

Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.

Open this study Sign up free