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Improving Outpatient Psychotherapy for Adults With Major Depressive and Anxiety Disorders Using Web-Based High-Frequency Monitoring and Feedback in Autosystemic Hypnotherapy: Protocol for a Two-Arm ABAB Crossed-Therapist Randomized Clinical Implementation Trial

Schiepek G, Wackernagel S

JMIR research protocols, 2026

100 participants

Abstract

Background: In recent years, routine outcome monitoring has been increasingly complemented by routine process monitoring in psychotherapy and other health care settings. Various approaches to therapy feedback exist, differing in assessment frequency, integration into the therapeutic process, and degree of personalization. In this study, we will use a procedure of high-frequency assessment through daily self-ratings, a standard process questionnaire, alongside a personalized questionnaire derived from case formulation, and frequent feedback interviews using visual diagrams to mirror the ongoing therapeutic processes.

Objective: This study aims to investigate the effectiveness of combining routine process monitoring with hypno-psychotherapy (autosystemic hypnotherapy) by comparing it to autosystemic hypnotherapy without process feedback in the outpatient treatment of mood disorders. It also seeks to examine process-outcome relationships and mechanisms of change through high-frequency self-assessments and session-based feedback.

Methods: This study is a randomized controlled trial with 2 arms, using within-therapist randomization (ABAB design) in outpatient psychotherapy. Participants are recruited offline via routine intake procedures. A total of 100 patients will be randomly assigned to one of the two conditions following a waiting period. The inclusion criterion is the existence of any mood disorder (major depressive disorder or anxiety disorder), assessed via a clinical…

How strong is the evidence?

Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design. Reported size: 100 participants or records.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

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