Septic shock caused by Elizabethkingia miricola in an elderly trauma patient: a case report and systematic literature review
Abstract
Objective: Elizabethkingia miricola is a rarely encountered pathogen in clinical settings, predominantly causing infections in immunocompromised individuals. To advance the understanding of E. miricola infection, we present a case of E. miricola infection and conduct a literature review.
Methods: We report a case of pulmonary infection caused by E. miricola in a 90-year-old trauma patient, marking the first documented instance of treatment with eravacycline. We also conducted a systematic review of the relevant literature. A comprehensive search was performed using the PubMed and Web of Science databases up to November 2024. A qualitative synthesis was conducted on all available case reports and case series related to E. miricola infections.
Results: A total of 63 cases from 21 studies were included in this systematic review. According to these case reports, infections caused by E. miricola most commonly occur in the lungs (34/63), bloodstream (6/63), and urinary tract (4/63). Risk factors for E. miricola infection include immunodeficiency, prolonged hospitalization in the intensive care unit (ICU), prolonged mechanical ventilation, and the use of broad-spectrum antibiotics. Notably, a considerable proportion of cases (17/63) are hospital-acquired.
Conclusion: Elizabethkingia miricola represents a rare but highly lethal opportunistic pathogen. Early identification and treatment with sensitive antibiotics are required to improve the prognosis of patients. The present case and…
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Evidence Hub reads this as a case series, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
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