Fungemia caused by Cyberlindnera fabianii: Clinical and microbiological insights from two fatal cases
Abstract
Cyberlindnera fabianii is a rare opportunistic yeast increasingly recognized as a cause of invasive infections. We report two fatal cases of C. fabianii fungemia in elderly patients with multiple comorbidities. Microbiological analysis revealed low minimum inhibitory concentrations (MICs) to amphotericin B and echinocandins, but variable susceptibility to fluconazole. One patient received antifungal therapy with limited response; in the second case, the pathogen was identified postmortem.
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