MRI of multiple sclerosis in Thai patients
Abstract
OBJECTIVE: Evaluate the MRI findings of multiple sclerosis (MS) in Thai patients and compare these with the McDonald criteria for dissemination in space.
MATERIAL AND METHOD: A retrospective study was performed by reviewing clinical and MRI records of patients attending MS clinic at Siriraj Hospital. Only patients with complete clinical and MRI data were included in the present study.
RESULTS: There were 25 patients included in the study. Twenty-four patients were females and 1 was male. The mean age was 35.24 years old (range 16-50). The disease duration was 1 month to 17 years after the onset. Twenty-three patients were diagnosed as relapsing-remitting MS, one as possible MS and one as clinical isolated syndrome. Analysis for CSF oligoclonal bands was performed in 22 cases with positive results in 6 cases (27.3%). The sites of involvement were optic neuritis (16 cases), spinal cord (14 cases), and brain (9 cases). Seventeen cases had MRI study at the early presentations, and 8 cases during subsequent relapses. In the 9 cases with brain symptoms, all had positive brain MRI. Ten cases (58.8%) had infratentorial lesions mostly found at the medulla. Most T2 lesions were found at juxtacortical and periventricular regions. Five in 9 cases (55.6%) with periventricular lesions had lesions not less than 3 mm and at least 3 lesions were found. There were 6 cases (35.3%) with, at least, nine T2 lesions. Most of the T2 lesions were oval shaped. Seven cases (41.2%) had black hole…
How strong is the evidence?
Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 25 participants or records.
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