Macular hole associated retinal detachment in presumed autosomal recessive bestrophinopathy: a retrospective observational series of TWO cases

Kannan NB, Vallinayagam M, Goswami A, Dara R

Retinal cases & brief reports, 2025

Abstract

Purpose: The objective of this study was to evaluate surgical outcome of presumed autosomal recessive bestrophinopathy with full-thickness macular hole and retinal detachment managed by pars plana vitrectomy.

Methods: This was a retrospective observational case series of two eyes of two patients who underwent 25 G pars plana vitrectomy with peeling of internal limiting membrane and SF6 tamponade and were assessed with respect to best-corrected VA, fundus photographs, and spectral domain optical coherence tomography.

Results: Type 1 closure of macular hole was achieved along with resolution of retinal detachment in both patients.

Conclusion: 25 G pars plana vitrectomy with peeling of internal limiting membrane and SF6 tamponade can result in favorable outcome in macular hole-associated retinal detachment in patients with presumed autosomal recessive bestrophinopathy.

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