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SinglePass electrocautery device for closure of lung and mediastinal biopsy: a case series of 5 patients

Techasith T, Jairam A, Park B, Mesipam A, Baker C, Cristiano B, Velling T, Patel T et al.

Frontiers in oncology, 2026

Abstract

Introduction: Percutaneous computed tomography (CT)-guided biopsy, including coaxial core needle biopsy (CCNB), has become the primary and preferred method for obtaining tissue samples in diagnosing or characterizing thoracic lesions, often in the lung or mediastinum. Despite advances in imaging and various approaches in reducing bleeding in the biopsy tract, pneumothorax and perilesional or lesional hemorrhage remain at the forefront of potentially serious complications. The increased risk that comes with requirements for additional tissue samples, both in size and in number, in the management of lung cancer is also a concern. Subsequent interventions may be required if significant pneumothorax or high-grade hemorrhage occurs and while death is a possible outcome with these procedures, it is rare.

Case presentation: This report of a series of five image-guided CCNB cases focused on lung and mediastinal mass lesions in which hemostasis and biopsy tract closure were obtained with the SinglePass Kronos electrocautery device. All biopsy procedures were successful, and no complications were reported through 30 days post-procedure. Imaging confirmed the absence of post-procedure pneumothorax and bleeding complications in all five cases.

Conclusion: The SinglePass electrocautery device is a potentially valuable tool in minimizing pneumothorax and hemorrhagic complications in percutaneous lung and mediastinal mass CCNB procedures.

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Evidence Hub reads this as a case series, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.

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