A swept-source optical coherence tomography study of the spectrum of laser pointer maculopathy
Abstract
Background: To evaluate the efficacy of swept-source optical coherence tomography (SS-OCT) in detecting the clinical spectrum of macular microstructure changes secondary to laser pointer injury (LPI), including their response to therapeutic intervention.
Methods: A retrospective study, including consecutive patients with LPI. Inclusion criteria were visual symptoms and biomicroscopic, OCT, and fundus fluorescein angiography (FFA) features of LPI. We used the SS-OCT for imaging and the swept-source optical coherence tomography angiography (SS-OCTA) to confirm or exclude the diagnosis of a choroidal neovascular membrane (CNV). We used FFA to confirm the diagnosis of a CNV whenever SS-OCT and SS-OCTA images were insufficient to establish its presence. The outcome measures were the morphological features in the macula secondary to LPI and the response of CNV to aflibercept.
Results: The study included 31 eyes of 22 patients. Ten patients (45%) were ≤ 15 years old. Laser pointer maculopathy (LPM) was bilateral in 9 patients (41%). The mode of injury was self-inflicted in 14 patients (64%). Central scotoma was the most common symptom reported by the patients. The mean baseline best-corrected visual acuity (BCVA) was 20/50. The mean follow-up period was 9.6 months. The mean final BCVA was 20/40. Acute stages of LPM were characterized by focal or diffuse disruption of the outer retinal layers, subretinal hyperreflective mound, anvil-shaped lesion, or the angular sign of Henle fiber…
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