Long-term surgical outcome of high myopic full-thickness macular hole without retinoschisis
Abstract
Background: To examine the clinical features and long-term surgical results of highly myopic full-thickness macular hole (FTMH) without retinoschisis.
Methods: We retrospectively assessed surgical outcomes of highly myopic patients who underwent vitrectomy with internal limiting membrane peeling and gas tamponade to treat FTMH without retinoschisis. Post-operative examinations were conducted at 1, 3, 6, and 12 months after surgery, with further follow-up intervals adjusted based on physician's discretion. Clinical features related to visual acuity and anatomical success, defined as hole closure without developing foveal atrophy, were assessed.
Results: Thirty-three eyes (30 patients) were included, and the mean follow-up period was 61.1 ± 48.8 months. Macular hole closure was achieved in 31 (93.9%) eyes, of which 16 (51.6%) developed foveal atrophy during follow-up. Eyes with anatomical success exhibited a significant better visual prognosis than those without during whole follow-up period (P ≤ 0.031), showing a significant postoperative visual improvement from baseline at 6 months, 12 months and final visit (P = 0.002, P < 0.001 and P = 0.013, respectively). Greater minimal macular hole diameter (P = 0.002) and the presence of posterior staphyloma (P = 0.040) were significantly related to anatomical failure, whereas longer axial length was significantly related to poorer final best-corrected visual acuity (P < 0.001).
Conclusions: Hole closure rate after vitrectomy in…
How strong is the evidence?
Evidence Hub reads this as a cohort study, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 30 participants or records.
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