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Central centrifugal cicatricial alopecia in Black men: A case series highlighting key clinical features in this cohort

Janet E. Lubov, U. Okereke, B. Clapp, J. Toyohara, Dolly Taiwò, Efe E Kakpovbia, K. Lo Sicco, P. Adotama

JAAD Case Reports, 2023

1 citation

Abstract

AGA: androgenetic alopecia CCCA: central centrifugal cicatricial alopecia INTRODUCTION Central centrifugal cicatricial alopecia (CCCA) is the most common cicatricial alopecia in Black patients and results in progressive hair loss and profound impact on well-being, that is associated with depression and poorer quality of life. Given the progressive nature of this condition, early and accurate diagnosis and treatment initiation are essential. Although CCCA has been well studied in Black women, there is a dearth of information regarding its manifestations in Black men. Furthermore, the history, physical examination, and trichoscopy patterns have been well described in female cohorts with CCCA; however, there is less information on special considerations for males with this condition. Given the predilection for CCCA to occur in female patients, providers may have a delayed diagnosis of CCCA in males with hair loss in the vertex scalp or may misdiagnose their condition for more common forms of hair loss such as androgenetic alopecia (AGA). Although AGA may exist concomitantly with CCCA, especially in male patients, and therapies, such as minoxidil, can be used to increase hair density in both conditions, it is important to identify CCCA correctly to initiate additional anti-inflammatory therapy as soon as possible. Herein, we present 3 cases of biopsy-supported CCCA in Black men, along with a review of pertinent clinical, trichoscopic, and histopathologic findings of CCCA. All…

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