Simultaneous Bilateral Endobronchial Valve Insertion for Management of Persistent Air Leaks Secondary to Necrotising Pneumonia
Abstract
Pneumothorax is an abnormal communication between the tracheobronchial tree and the pleural space either as a result of a broncho‐pleural fistula or an alveolo‐pleural fistula. When the air leak from these fistulae persists beyond 5 days it is defined as a persistent air leak (PAL). Whilst surgical repair remains the standard of care, endobronchial valves (EBVs), established for bronchoscopic lung volume reduction (BLVR), are emerging as a minimally invasive alternative. Current data supporting the use of EBVs in PAL are limited to case reports and small retrospective case series. This report details a rare case of bilateral PAL secondary to necrotising pneumonia in a critical ill patient, successfully managed with simultaneous bilateral EBV placement, highlighting the feasibility and clinical efficacy of this approach.
How strong is the evidence?
Evidence Hub reads this as a case series, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
Read the paper
Related studies
- Penicillins for Treatment of Pneumococcal Pneumonia: Does In Vitro Resistance Really Matter?
- Thiophenes—Naturally Occurring Plant Metabolites: Biological Activities and In Silico Evaluation of Their Potential as Cathepsin D Inhibitors
- Inhalable Mannosylated Rifampicin–Curcumin Co-Loaded Nanomicelles with Enhanced In Vitro Antimicrobial Efficacy for an Optimized Pulmonary Tuberculosis Therapy
- Development and validation of microbial bioassay for quantification of Levofloxacin in pharmaceutical preparations
- GC-MS Analysis and Biomedical Therapy of Oil from n-Hexane Fraction of Scutellaria edelbergii Rech. f.: In Vitro, In Vivo, and In Silico Approach
- Propranolol, chlorpromazine and diclofenac restore susceptibility of extensively drug-resistant (XDR)-Acinetobacter baumannii to fluoroquinolones
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.