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Autologous Tenon's capsule for post-vitrectomy macular hole closure: A case report

Maryam Al-Muzaffar, Anant Pai, Osman F. Abdelzaher, H. A. Serhan

American Journal of Ophthalmology Case Reports, 2026

Abstract

Purpose To report the anatomical and visual outcomes of autologous Tenon's capsule patch grafting for closure of a large post-vitrectomy full-thickness macular hole. Observations A 63-year-old female with proliferative diabetic retinopathy presented with decreased vision in the right eye. Optical coherence tomography demonstrated a 1112 μm full-thickness macular hole. Due to prior internal limiting membrane peeling, insufficient tissue remained for conventional techniques, an autologous Tenon's capsule graft was harvested through a limited conjunctival peritomy and positioned on the macular defect. Silicone oil tamponade was used to stabilize the graft. One-month follow-up demonstrated anatomical closure of the macular hole, which remained stable at 6 months. Visual acuity improved from hand motion preoperatively to 1/60 at final follow-up. Conclusions and importance Autologous Tenon's capsule patch grafting may serve as a useful surgical alternative for large post-vitrectomy macular holes when internal limiting membrane tissue is unavailable.

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