Chlamydia psittaci pneumonia without cough: recovery, case report and literature review
Abstract
Objectives: We report a case of Chlamydia psittaci pneumonia in a patient presenting with high fever and generalized myalgia but no cough. As infections with Chlamydia psittaci are potentially misdiagnosed and non-responsive to empirical antibiotic treatment, this report aims to enhance the awareness among the healthcare providers.
Methods: A 34-year-old male patient developed high fever and fatigue after exposure to poultry. He presented to the hospital for treatment. Chest computed tomography (CT) showed a high-density shadow in the deep area of the left lower lung. Sputum culture returned negative. Empirical treatment with multiple antibiotics was given. No improvement was observed in the patient's condition. Next-generation sequencing (NGS) was performed on bronchoalveolar lavage fluid. It confirmed the diagnosis of Chlamydia psittaci infection. The lesion was located deeply. The clinical team promptly adjusted the antibiotic regimen. Intensive pulmonary rehabilitation training was added simultaneously. It facilitated the drainage of deep-seated sputum. The patient finally achieved complete recovery and was discharged.
Results: This case report indicates that in patients with high fever, clinicians should first determine the etiological factors and identify the lesion site. Accurate diagnosis can thus be achieved. In this case, the lesion was deeply located in the lung. Even with sensitive antibiotics, complete elimination of the lesion was difficult. Therefore, active…
How strong is the evidence?
Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
Read the paper
Related studies
- Penicillins for Treatment of Pneumococcal Pneumonia: Does In Vitro Resistance Really Matter?
- Thiophenes—Naturally Occurring Plant Metabolites: Biological Activities and In Silico Evaluation of Their Potential as Cathepsin D Inhibitors
- Inhalable Mannosylated Rifampicin–Curcumin Co-Loaded Nanomicelles with Enhanced In Vitro Antimicrobial Efficacy for an Optimized Pulmonary Tuberculosis Therapy
- Development and validation of microbial bioassay for quantification of Levofloxacin in pharmaceutical preparations
- GC-MS Analysis and Biomedical Therapy of Oil from n-Hexane Fraction of Scutellaria edelbergii Rech. f.: In Vitro, In Vivo, and In Silico Approach
- Propranolol, chlorpromazine and diclofenac restore susceptibility of extensively drug-resistant (XDR)-Acinetobacter baumannii to fluoroquinolones
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.