Three-dimensional reconstruction of the "bright ring" echogenicity from porcine blood upstream in a stenosed tube
Abstract
To investigate the echogenicity variation due to blood flow disturbance near a stenosis under pulsatile flow, a series of in vitro experiments were performed in a rigid tube with an eccentric stenosis of 70% area reduction in a mock flow loop. An ultrasonic B-mode with a Doppler spectrogram was used to correlate echogenicity with flow speed and stroke rate. This paper reports echogenicity variation upstream of a stenosis under pulsatile flow. The experimental results showed that blood flow disturbed by the stenosis affects echogenicity and red blood cell rouleaux upstream. A hypoechoic "black hole" was shown at the center of the stream at systole. During diastole, the "bright ring" in cross-sectional images was observed as eddy-like or parabolic profiles in longitudinal images. These images could be reconstructed into a 3-dimensional animation, providing a better understanding of dynamic changes of the rouleaux distribution upstream of a stenosis under pulsatile flow.
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Evidence Hub reads this as a editorial / letter, done in animal, not in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
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