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Metformin: a review of its potential indications

Wang YW, He SJ, Feng X, Cheng J, Luo YT, Tian L, Huang Q

Drug design, development and therapy, 2017

321 citations

Abstract

Abstract: Metformin is the most commonly prescribed drug for type 2 diabetes mellitus. In recent years, in addition to glucose lowering, several studies have presented evidence suggesting some potential role for metformin, such as antitumor effect, antiaging effect, cardiovascular protective effect, neuroprotective effect or an optional treatment for polycystic ovary syndrome. This paper will critically review the role of metformin to provide reference for doctors and researchers. Keywords: metformin, antitumor effect, antiaging effect, cardiovascular protective effect, neuroprotective effect, PCOS

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