Levels of IL‐1β, MMP‐8, and MMP‐9 in the Saliva of Subjects With Periodontitis: A Systematic Review and Meta‐Analysis
Abstract
Proinflammatory cytokines and enzymes responsible for tissue destruction are important in the development of periodontitis. This study compared salivary concentrations of interleukin‐1 beta (IL‐1β), matrix metalloproteinases (MMP‐8), and (MMP‐9) in individuals with and without periodontitis to evaluate their diagnostic utility as potential biomarkers.
How strong is the evidence?
Evidence Hub reads this as a systematic review. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid.
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