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Prevalence and risk factors for loneliness among individuals with diabetes: a systematic review and meta-analysis

Anggi Lukman Wicaksana, Renny Wulan Apriliyasari, Pei-Shan Tsai

Systematic Reviews, 2025

6,036 participants · 6 citations

Abstract

Loneliness is more pronounced in individuals with diabetes; however, limited studies have investigated loneliness and its risk factors. This study estimated the pooled prevalence of loneliness and identified its risk factors in individuals with diabetes. A systematic review and meta-analysis of observational studies was conducted. CINAHL, Cochrane, Embase, PubMed, Scopus, and Web of Science databases were searched from their inception to September 22, 2023. We systematically searched and analyzed 10 studies involving 6036 individuals with diabetes to determine the pooled prevalence of loneliness. Five studies provided information on risk factors. Using a random-effects model, we calculated prevalence rates and odds ratios with 95% confidence intervals. The overall prevalence of loneliness was 31.1% and severe loneliness was 4.6%. White race, lower education level, middle income, low income, longer diabetes duration, lower cognitive function, living alone, previous loneliness experience, and depression were identified as significant risk factors for loneliness in individuals with diabetes. Over 30% of individuals with diabetes experience loneliness. Several sociodemographic factors, low cognitive function, and depression are risk factors for loneliness.

How strong is the evidence?

Evidence Hub reads this as a meta-analysis, done in people. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid. Reported size: 6,036 participants or records.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

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