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Perioperative methadone for posterior spinal fusion in adolescents: Results from a double‐blind randomized‐controlled trial

Roger A Fons, K. Hainsworth, J. Michlig, Megan Jablonski, M. Czarnecki, Steve Weisman

Paediatric anaesthesia, 2024

14 citations

Abstract

Posterior spinal fusion is the most common surgical procedure performed for correction of adolescent idiopathic scoliosis in the United States. Intraoperative methadone has been shown to improve pain control in adult patients undergoing complex spine surgery, and current pediatric studies show encouraging results; however, prospective randomized‐controlled trials are lacking in the pediatric literature.

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Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design.

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