Antibodies everywhere: The spectrum of IgG4-related disease—A case series and literature review
Abstract
Introduction: IgG4-related disease (RD) is now known to affect multiple organs, including the gastrointestinal system, kidneys, lungs, and retroperitoneum. Diagnosis of IgG4-RD involves a combination of clinical, radiological, serological, and histopathological findings.
Case Series: This case series underscores the importance of recognizing IgG4-RD as a potential etiology of diseases of unclear pathology with patient presentations, including pancreatitis, cholangitis, renal and mesenteric ischemia, back mass, and interstitial lung disease.
Conclusion: Further, we discuss the histological findings, imaging, serology, other organ involvement and response therapy (HISORt) criterion of diagnosis, and treatment options including steroid-sparing agents.
Read the paper
Related studies
- Improving sleep quality leads to better mental health: A meta-analysis of randomised controlled trials
- Tocilizumab in patients with severe COVID-19: a retrospective cohort study
- A new aging measure captures morbidity and mortality risk across diverse subpopulations from NHANES IV: A cohort study
- Fruit, vegetable, and legume intake, and cardiovascular disease and deaths in 18 countries (PURE): a prospective cohort study
- Are noise and air pollution related to the incidence of dementia? A cohort study in London, England
- Long COVID symptoms and duration in SARS-CoV-2 positive children — a nationwide cohort study
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.