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Intravenous iron in patients with heart failure and iron deficiency: an updated meta‐analysis

F. Graham, P. Pellicori, P. Kalra, I. Ford, D. Bruzzese, J. Cleland

European Journal of Heart Failure, 2023

118 citations

Abstract

For patients with heart failure (HF) and iron deficiency (ID), randomized trials suggest that intravenous (IV) iron reduces hospitalizations for heart failure (HHF), but uncertainty exists about the effects in subgroups and the impact on mortality. We conducted a meta‐analysis of randomized trials investigating the effect of IV iron on clinical outcomes in patients with HF.

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Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design.

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