A case of gastric cancer with virchow and para-aortic node metastasis treated successfully by neo-adjuvant chemotherapy with S-1/CDDP
Abstract
A 61-year-old female visited our hospital with the complaint of a left cervical hard tumor. Systemic examination revealed advanced gastric carcinoma with nodal involvement of para -aortic and Virchow's lymph nodes. Neoadjuvant chemotherapy with S-1/cisplatin(CDDP)combination therapy was scheduled. Three courses of chemotherapy resulted in marked tumor regression and a reduction of lymph nodes. Total gastrectomy and D2+para-aortic node dissection were performed. The histological examination revealed complete disappearance of cancer cells in the gastric and nodal specimens, confirming a pathological complete response. The patient underwent postoperative adjuvant chemotherapy, and has been alive 5 years postoperatively without recurrence.
How strong is the evidence?
Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
Read the paper
Related studies
- Combining in silico and in vitro approaches to identification of potent inhibitor against phospholipase A2 (PLA2)
- In silico and in vitro studies: investigating the chemical composition, DFT, molecular docking, and dynamic simulation of Satureja candidissima (Munby) Briq essential oil as a potential antibacterial agent
- Quercetin combined with ciprofloxacin and gentamicin inhibits biofilm formation and virulence in Staphylococcus aureus
- In silico study of the mechanism of action, pharmacokinetic and toxicological properties of some N-methylanthranilates and their analogs
- Anticonvulsant Effects of Citronellal, Daidzin, and Phytol, Possibly Through GABAA Receptor and Voltage-Gated Sodium Channel Interaction Pathways: In Vivo and In Silico Studies
- 2-Phenylcyclopropylmethylamine (PCPMA) Derivatives as D3R-Selective Ligands for 3D-QSAR, Docking and Molecular Dynamics Simulation Studies
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.