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International guidelines for the assessment of chronic kidney disease

Delanaye P, Jouret F, Cavalier É

Revue medicale de Liege, 2025

Abstract

The new KDIGO («Kidney Disease Improving Global Outcomes») 2024 guidelines on chronic kidney disease (CKD) provide significant updates. They reaffirm the importance of the glomerular filtration rate (GFR) and of the urine albumin-to-creatinine ratio (ACR) for diagnosing and classifying CKD. CKD is defined by a GFR 30 mg/g and/or persistent renal abnormalities for at least three months. The main innovation is the preferential use of equations combining creatinine and cystatin C to estimate GFR, although cystatin C assay may not always be available or reimbursed. The guidelines also recommend the EKFC («European Kidney Function Consortium») equations, particularly suited to Europe and applicable to all age groups. ACR remains a key indicator for assessing the risk of CKD progression and the response to nephroprotective treatments. The use of the «Kidney Failure Risk Equation» is encouraged to estimate the risk of kidney failure and guide clinical decisions.

Les nouvelles directives KDIGO («Kidney Disease Improving Global Outcomes») 2024 concernant la maladie rénale chronique (MRC) apportent des mises à jour importantes. Elles confirment l’importance du débit de filtration glomérulaire (DFG) et du rapport albumine/créatinine urinaire (ACR) pour le diagnostic et la classification de la MRC. La MRC est définie par un DFG 30 mg/g et/ou des anomalies rénales structurelles persistantes pendant au moins 3 mois. La principale nouveauté réside dans l’utilisation préférentielle des…

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