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Acupuncture improves migraine and quality of life in patients with migraine: a systematic review with meta-analysis

Ting-ting Lu, Yang Yang, Jie-Yun Li, Liang-Ping Lu, Jie Liu

Systematic Reviews, 2025

2,295 participants · 4 citations

Abstract

Objective: A systematic review (SR) with meta-analysis (MA) was conducted to investigate acupuncture's efficacy in treating migraine and its impact on quality of life.

Methods: PubMed, Embase, Cochrane Library, Chinese Biomedical Databases, China National Knowledge Infrastructure, VIP, and Wanfang were searched for randomized controlled trials (RCTs) from database inception to May 31, 2024. Statistical analyses were performed with Review Manager 5.4.1.

Results: We included 23 RCTs comprising 2295 patients. Compared with sham acupuncture, acupuncture reduced migraine duration (MD: - 4.36 h; 95% CI: - 8.07, - 0.64), the number of mean migraine attacks (MD: - 0.82; 95% CI: - 1.57, - 0.08), days with migraine per 4 weeks (MD: - 1.38; 95% CI: - 2.16, - 0.60), improved MSQ restrictive subscale (MD: 13.73; 95% CI: 5.60, 21.87) and MSQ emotional function (MD: 9.93; 95% CI: 2.64, 17.22). Compared with pharmacological treatment, acupuncture improved MSQ restrictive subscale (MD: 5.69; 95% CI: 2.15, 9.23) and MSQ emotional function (MD: 7.14; 95% CI: 1.62, 12.66). Compared with waiting lists, acupuncture reduced the number of mean migraine attacks (MD: - 0.80; 95% CI: - 1.12, - 0.48), days with migraine per 4 weeks (MD: - 2.10; 95% CI: - 2.74, - 1.46), and improved MSQ restrictive subscale (MD: 9.40; 95% CI: 4.82, 13.98) and MSQ emotional function (MD: 9.00; 95% CI: 4.52, 13.48).

Conclusions: Acupuncture was significantly associated with reduced migraine duration, number of migraine…

How strong is the evidence?

Evidence Hub reads this as a meta-analysis, done in people. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid. Reported size: 2,295 participants or records.

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