Evidence Hub

Dental Care for Patients With Congenital Bleeding Disorder: A Systematic Review

Afsary Jahan Khan, S. R. Riyadh, M. Al-Naser, Norjehan Yahaya, Mas Suryalis Ahmad, A. F. Omar, Altaf H Shah

Special Care in Dentistry: managing special patients, settings, and situations, 2025

Abstract

INTRODUCTION

Dental management in patients with congenital bleeding disorder (CBD) can be complex, as even minor oral surgery may precipitate prolonged bleeding. Effective treatment requires a thorough medical and dental history evaluation, including pre-, intra-, and post-operative planning. This systematic review (SR) aims to analyze data on CBD patients, including age, treatment techniques, outcomes, and recommendations for minimizing bleeding risks.

MATERIALS AND METHODS

A comprehensive electronic search was conducted across five databases-PubMed via MEDLINE, Embase, Cochrane Library, Scopus, and Web of Science-using expert-validated keywords. Manual searches complemented the selection process, covering studies from first January 2009, to December 31, 2024. The SR followed PRISMA guidelines, with PICOS parameters defining study inclusion criteria.

RESULTS

A total of 1221 records were identified, with three additional articles from manual and grey literature searches, resulting in 12 publications for data extraction and thematic analysis. Findings showed that patients with various CBD from seven countries underwent different dental procedures with structured pre-, intra-, and post-operative management, leading to positive outcomes.

CONCLUSIONS

This SR highlights the importance of standardized care protocols and multidisciplinary collaboration in ensuring safe dental treatment for CBD patients. Advanced hemostatic methods and tailored interventions significantly minimized…

How strong is the evidence?

Evidence Hub reads this as a systematic review, done in people. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

Read the paper

Related studies

Go deeper in Evidence Hub

Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.

Open this study Sign up free