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Prevalence and Predictors of Depression Symptoms Among Afghan Hypertensive Patients: Secondary Analysis of a Multi-Center Cross-Sectional Study

Muhammad Haroon Stanikzai, M. Zafar, Khalid Akbari, Ahmad Haroon Baray, Hadia Sayam

Integrated Blood Pressure Control, 2024

853 participants · 6 citations

Abstract

Background Although depression is a frequently occurring mental disorder in patients with hypertension, little is known about the symptoms of depression among Afghan hypertensive patients. Objective This study aimed to analyze the prevalence and predictors of depression symptoms among Afghan hypertensive patients. Methods This was a secondary analysis of a multi-center cross-sectional study conducted between August and December 2022 across three major provinces in Afghanistan. Socio-demographic and clinical characteristics of the eligible participants were used in the analysis. A score of ≥ 5 on the PHQ-9 (Patient Health Questionnaire) was considered the cut-off point for labeling hypertensive patients as screening positive for depressive symptoms. We performed binary logistic regression to determine the predictors of depression symptoms among hypertensive patients. Results Out of 853 hypertensive patients, 51.8% (95% CI: 48.4–55.2%) had depressive symptoms. Binary logistic regression revealed that low monthly household income [AOR=1.42, 95% CI (1.01–1.97), low education level [2.41 (1.57–3.71)], physical inactivity [1.81 (1.22–2.71)], poor blood pressure control [2.41 (1.57–3.71)], and the presence of medical comorbidity [1.59 (1.15–2.19)] were the predictors of depression symptoms. Conclusion This study showed a high prevalence of depressive symptoms among Afghan hypertensive patients. Moreover, we found that low monthly household income, physical inactivity, low education…

How strong is the evidence?

Evidence Hub reads this as a secondary / pooled analysis, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 853 participants or records.

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