Prevalence of Uropathogens and Its Antibiogram among Diabetic and Non Diabetic Patients
Abstract
Objectives: The objectives of the research was to evaluate the prevalence of uropathogens, their resistance pattern, and association factors of UTI among diabetic and non-diabetic patients. Material and Methods: A cross-sectional study was conducted during the year Sep-2022 to Jan-2024, among 1048 adult patients from SMIMER (Smimer Hospital and Medical college, Surat) and other private laboratory from Surat area. Using recommended culture methods, Clean-catch midstream urine samples were collected and examined for the presence of uropathogens and their antimicrobial susceptibility pattern.
Results: The highest prevalence of uropathogens were Escherichia coli (49%), Klebsiella spp (39.2%) and Candida (fungus) (13.2%). Most of the uropathogens were sensitive to nitrofurantoin, cefixime and amikacine in diabetic and most of the uropathogens were sensitive to meropenem, amikacine and levofloxacin in non-diabetic patients. Whereas resistant to Ampicillin/Sulbactam, Cefuroxime and Co-Trimoxazole (Sulpha/Trimethoprim) in diabetic patients, same as resistant to amikacin and netillin drug in non diabetic patients.
Conclusion: The prevalence of UTI and most commonly used antibiotics among diabetic and non-diabetic patients is compared with published paper. Urine analysis and culture should be performed in all diabetic and non diabetic patients. Most common uropathogens is E.coli in both groups.
How strong is the evidence?
Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 1,048 participants or records.
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