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Orofacial Manifestations in Patients Diagnosed With Malaria in the Western Brazilian Amazon: A Cross-Sectional Study

Antonio Arlen da Silva Freire, L. A. Valadas, C. M. Tapety, R. Melo, Emmanuel Arraes de Alencar

Special Care in Dentistry: managing special patients, settings, and situations, 2025

38 participants

Abstract

OBJECTIVE

Considering the little evidence about the action of the dentist in the management of patients diagnosed with malaria, this study aimed to analyze the main orofacial changes that affect these patients.

MATERIALS AND METHODS

This is a cross-sectional study where 38 patients diagnosed with malaria are included. An extraoral physical examination was carried out using the diagnostic criteria for temporomandibular disorders instrument. Signs of changes in the oral cavity were detected through intraoral physical examination.

RESULTS

The xerostomia was measured according to the xerostomia inventory scale score (XISS). In this study participated 33 men (87%) and 5 women (13%), with a notable diagnosis of Plasmodium vivax (n = 26). When assessed, the incidence of orofacial changes in the sample studied stands out as myalgia in the chewing muscles (92.1%) and arthralgia in the temporomandibular joint (65.7%). In this study, the results show that there is an association between types of malaria and dysgeusia (p = 0.01).

CONCLUSION

Given the data obtained, it appears that the patients most affected by the infection are men, and the most commonly found changes are color changes in the oral mucosa, petechiae, xerostomia, arthralgia, myalgia in the chewing muscles, and dysgeusia, even without prior use of antimalarial medication.

How strong is the evidence?

Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 38 participants or records.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

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