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Aeromonas hydrophila Osteomyelitis of the Femur in a 14-Year-Old Girl on Antituber-cular Therapy: A Rare Presentation

Mohit Gandhi, Zeeshan Khalil

International Journal of Medical and Biomedical Studies, 2026

Abstract

Introduction: Aeromonas hydrophila is an uncommon cause of musculoskeletal infections, particularly in immunocompetent pediatric patients [1]

Case Presentation: We report a 14-year-old girl on antitubercular therapy (ATT) who developed chronic non-healing medial thigh wound and femoral osteomyelitis following an aspiration procedure. MRI showed intramedullary osteomyelitis with multiloculated intramuscular collections. Surgical incision and drainage with cortical windowing was performed. Culture revealed Aeromonas hydrophila, sensitive to trimethoprim- sulphamethoxazole, levofloxacin, and gentamicin. She improved well with targeted therapy and continued ATT.

Conclusion: Atypical pathogens should be considered in osteomyelitis cases with prior invasive procedures or chronic systemic illness. Early surgical intervention and organism-specific antibiotics lead to good outcomes.

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