Antimicrobial use guidelines for canine pyoderma by the International Society for Companion Animal Infectious Diseases (ISCAID)
Abstract
BACKGROUND: Canine pyoderma is one of the most common presentations in small animal practice, frequently leading to antimicrobial prescribing. OBJECTIVES: To provide clinicians with antimicrobial treatment guidelines for staphylococcal pyoderma, including those involving meticillin-resistant staphylococci. Guidance on diagnosing surface, superficial and deep pyoderma and their underlying primary causes, is included. Recommendations aim to optimise treatment outcomes while promoting responsible antimicrobial use. MATERIALS AND METHODS: Evidence was gathered from a systematic literature review of English-language treatment studies for canine pyoderma up to 23 December 2023. Quality was assessed using SORT criteria and combined with authors' consensus evaluation. Recommendations were voted on in an iterative process, followed by a Delphi-style feedback process before final agreement by the authors. RESULTS: Cytology should be performed in all cases before antimicrobials are used. Topical antimicrobial therapy alone is the treatment-of-choice for surface and superficial pyodermas. Systemic antimicrobials should be reserved for deep pyoderma and for superficial pyoderma when topical therapy is not effective. Systemic therapy, with adjunctive topical treatment, is initially provided for 2 weeks in superficial and 3 weeks in deep pyoderma, followed by re-examination to assess progress and manage primary causes. First-choice drugs have expected efficacy against the majority of…
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Evidence Hub reads this as a systematic review, done in animal, not in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
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