Comparative Efficacy and Safety of Pharmacological Prophylactic Agents for Migraine in Children and Adolescents: A Systematic Review and Bayesian Network Meta-Analysis
Abstract
Abstract Background Migraine is a leading cause of recurrent disabling headache in children and adolescents, yet most prophylactic agents have failed to outperform placebo, and head-to-head trials are scarce. We conducted a network meta-analysis (NMA) comparing the efficacy and safety of pharmacological migraine prophylaxis in pediatric patients. Methods We searched PubMed, Cochrane CENTRAL, Scopus, and Embase for RCTs of migraine prophylaxis in patients CRD420261454779 ]
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