Phase I Pharmacokinetic and Safety Study of Intravenous Topiramate in Adult Patients
Abstract
The aims of this study are to determine, in adult patients on maintenance topiramate therapy, the steady-state pharmacokinetics and safety of orally and intravenously administered topiramate.
Conditions: Epilepsy, Migraines.
Primary outcome: Safety as measured by the occurrence of adverse events.
Enrollment: 20 participants.
How strong is the evidence?
Evidence Hub reads this as a clinical trial, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 20 participants or records.
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