Impact of promoting physical exercise on migraine - A video-based randomized clinical trial
Abstract
INTRODUCTION
Migraine significantly impacts quality of life, and a substantial proportion of subjects experience refractory migraine. Non-pharmacological strategies, such as physical exercise, have shown potential benefits in headache control. This study aims to evaluate the effectiveness of a video-based educational intervention in promoting physical activity and improving migraine-related outcomes.
METHODS
A single-centre, single-blinded randomized clinical trial included 65 migraine subjects from a tertiary hospital in Porto, Portugal. Participants were stratified by age and randomized into an intervention group, receiving seven educational videos on exercise benefits over three months, or a control group, receiving usual care. Assessments were conducted at baseline (T0) and six months later (T6; three months after intervention). Primary outcome included the Headache Impact Test - 6 item (HIT-6) score; secondary outcomes included migraine frequency, acute medication use, and three Physical Activity Indices. Preventive treatments followed standard clinical practice, with physicians blinded to group allocation. Statistical analyses included between-group and within-group comparisons (p ≤ 0.05).
RESULTS
Among 105 randomized subjects, 65 completed the study (61.9 %; 32 out of 53 in the intervention group vs. 33 out of 52 in the control group). Baseline sociodemographic and headache characteristics were comparable between groups, including the number and the type of preventive…
How strong is the evidence?
Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design. Reported size: 105 participants or records.
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