Differences Among Veterans With Chronic Overlapping Pain Conditions and Other Chronic Pain: Baseline Results From the LAMP Pain Management Trial
Abstract
Background: Chronic overlapping pain conditions (COPCs) are a constellation of disorders posited to share an underlying pain mechanism (nociplastic pain). Unfortunately, individuals with COPCs are under-represented in clinical research. The current study aimed to determine COPC prevalence among participants enrolled in a pragmatic clinical trial and compare those with COPCs to those with non-COPCs across several domains.
Methods: Learning to Apply Mindfulness to Pain (LAMP) study baseline data of veterans with chronic pain (N = 811) were utilised. COPC diagnoses were determined using ICD-10 codes within electronic health records. Group differences across pain and functioning-related domains were compared with and without adjustment for age and gender.
Results: Among participants with COPCs (54%), most were diagnosed with only one COPC (74%). Chronic lower back pain (71%) and migraine (28%) were the most common. Participants with COPCs were younger and more likely to be female relative to those with non-COPCs. The COPC subset was also more likely to be diagnosed with PTSD, depressive disorders and sleep disorders (p < 0.05). Those with COPCs also reported greater pain severity and interference, more impaired health-related quality of life, greater pain catastrophising and lower pain self-efficacy than participants without COPCs (p < 0.05).
Conclusions: COPCs were common among a sample of veterans in a pragmatic clinical trial. Several baseline differences emerged indicating…
How strong is the evidence?
Evidence Hub reads this as a clinical trial, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 811 participants or records.
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