Therapeutic Efficacy of Classical Ayurvedic Shamana Chikitsa And Sira Vyedhana in Ardhavabhedaka W.S.R to Migraine: A Prospective Clinical Case Series
Abstract
Background
Ardhavabhedaka is one among the eleven Shirorogas described in Ayurvedic classics and clinically resembles
migraine headache.¹ Migraine is a chronic disabling neurovascular disorder characterized by recurrent attacks of
unilateral throbbing headache associated with nausea, vomiting, photophobia and phonophobia.² According to the
Global Burden of Disease study, migraine is one of the leading causes of years lived with disability worldwide.³
Contemporary management includes analgesics, triptans, beta blockers and antidepressants; however, recurrence,
medication dependency and adverse effects remain major concerns.⁴ Ayurveda provides a holistic therapeutic
approach through Shamana Chikitsa, Ghrita preparations and para-surgical interventions such as Sira Vyedhana.⁵
Aim To evaluate the efficacy of Avipatti Churna, Dhatryadi Kashayam, Godanti Bhasma, Mahatiktaka Ghrita and Sira
Vyedhana in the management of Ardhavabhedaka w.s.r to Migraine.
Materials and Methods
A prospective open-label interventional case series study was conducted on 10 patients diagnosed with
Ardhavabhedaka/Migraine attending the OPD and IPD of the Department of Kayachikitsa, GAM Puri. Patients
received Avipatti Churna 3 g, Dhatryadi Kashayam 15 ml, Godanti Bhasma 250 mg and Mahatiktaka Ghrita 1
teaspoon twice daily before food for 90 days. Sira Vyedhana at Sankha-Lalata Sandhi was performed once weekly for
28 days. Assessment was carried out using Visual Analogue Scale (VAS), frequency and duration…
How strong is the evidence?
Evidence Hub reads this as a case series, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health. Reported size: 10 participants or records.
Read the paper
Related studies
- Calcium Ions in the Physiology and Pathology of the Central Nervous System
- AI-powered in silico twins: redefining precision medicine through simulation, personalization, and predictive healthcare
- In silico functional, structural and pathogenicity analysis of missense single nucleotide polymorphisms in human MCM6 gene
- In Silico drug repurposing pipeline using deep learning and structure based approaches in epilepsy
- Targeting serotonin receptors with phytochemicals – an in-silico study
- In silico exploration of anti-prostate cancer compounds from differential expressed genes
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.