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Late lyme neuroborreliosis with multifocal neurological symptoms and meningeal enhancement

Bundgård J, Karlsson WK, Stenør CPM, Ravn P

Ugeskrift for laeger, 2026

Abstract

Late neuroborreliosis is rare in Denmark and can easily be mistaken for other neuroinflammatory or neoplastic diseases. In this case report, a 55-year-old woman with previous breast cancer presented with symptoms of meningoradiculitis, cranial nerve palsies, encephalomyelopathy, and cerebral vasculitis. Brain MRI revealed nodular meningeal enhancement around the brainstem and cervical spine cord. A lumbar puncture confirmed the diagnosis of neuroborreliosis. The patient was treated with ceftriaxone and doxycycline and showed recovery within the following months.

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