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Case report: Treatment of temporomandibular joint disorder pain with V3 nerve block procedure

Zeldich D, Calderon N, Goor-Aryeh I, Lichtenstein GR

Headache, 2026

Abstract

A 38-year-old woman with temporomandibular joint dysfunction (TMJD) and chronic migraine presented with refractory TMJD-related pain. Conservative treatments and prior injections provided only short-term relief. To achieve longer lasting pain reduction, an ultrasound-guided V3 nerve block was performed, targeting the mandibular nerve with a 4-mL injection of 1% lidocaine. The patient experienced immediate pain relief and sustained improvement. Encouraged by results on the right side, she underwent the same procedure on the left, achieving identical relief. Despite unchanged migraine frequency, TMJD pain resolution significantly enhanced her quality of life, demonstrating the efficacy of ultrasound-guided V3 nerve blocks.

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